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Improve Feed Bio-Security with ACTIVATE DA

Importance of Feed Biosecurity

Feed hygiene is a critical biosecurity control point for pathogenic bacteria, like Salmonella. However, recent research shows that viruses can survive in complete feed. A study by Dee et al. evaluated survival of several viruses that affect pork production in common feed materials and identified significant risks, highlighting a biosecurity gap beyond pathogenic bacteria.Most farms have a biosecurity program in place to protect and prevent diseases from entering and harming their animals. Deterrents are provided to prevent viral entry to the farm by installing spray systems, showers and changing rooms, foot and wheel dips, and also controlling animal and personnel movement in the farm. But one aspect often overlooked by producers is that not only farms should be involved in biosecurity, feed mills should also have their own biosecurity program as they can also easily spread viruses through feed contamination.

Viruses are small infectious agents that can only survive in the tissues of living things. Their survival outside the host, will depend on specific carriers of the virus. During the PEDv outbreak of 2013 in the US, it has been deduced that the virus came from contaminated feed and raw materials, and has caused a loss of 7 million pigs or 10% of the annual pig population. The current outbreak of African swine fever (ASF) in China has been also attributed to feed and raw material contamination thus making it more challenging to control the spread. Both PEDv and ASF, will have devastating effects in pork production, as both viruses affect performance and increase mortality dramatically. The need to control the spread of both PEDv, ASFv and other important viruses have been on the forefront of every pork producers mind.

How do major viral spread happens?

  • Contaminated materials & transport vehicles
  • Direct contact with infected pigs
  • Intake of infected food residues & meat products
  • Soft ticks

African Swine Fever (ASFv)

African Swine Fever (ASF) is a highly contagious viral swine disease in swine.The disease has generally been present in countries of sub-Saharan Africa. In August 2018, it was reported for the first time in China, and in September 2018 it was detected in wild boar in western Europe (Belgium). In January 2019 Mongolia also first reported ASF, and in February 2019 it has been detected in Vietnam.

Prevention through Feed Biosecurity


Research with organic acids has shown antimicrobial effects and performance improvements during bacterial challenges. In vitro research showed an effect of organic acid on reducing viruses in feed materials in a transboundary shipping model5. To demonstrate if the same organic acid effect could be demonstrated in an animal model, a trial was conducted to evaluate the role of ACTIVATE® DA on the survival of PEDV and PRRS strain 174 survival in swine feed and evaluate the role of ACTIVATE® DA on the manifestation of clinical symptoms and the performance of swine facing viral challenges.


ACTIVATE® DA nutritional feed acidifier containing a blend of organic acid including a highly bio-available source of HMTBa. Studies support that the use of ACTIVATE DA in feed can reduce livability of viruses and bacteria and effectively provides a methionine source for pigs during stressful conditions.

Mode of Action: ACTIVATE DA has a high concentration of active ingredients including organic acids & HMTBa which works to lower pH and increase the sensitivity of DNA by altering the virus capsid loss of structural protein. This maximizes the synergistic anti-viral effect against variety of viruses.




FORMYCINE® preservative pre-mix is a powerful source of raw material and finished feed protection. Its unique blend of ingredients provides unsurpassed protection through targeted modes of action. Beyond its effective control of bacteria, mold, viruses and yeast, FORMYCINE is fast-acting and does not leave residue in meat or final products.

Mode of Action: Formaldehyde and propionic acid, the active ingredients in FORMYCINE GOLD Px, work together to rapidly kill contaminated microbial and control bacteria and viruses while maintaining pH in the GI tract.



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Recent Updates


Novus Feed Biosecurity Forum, Vietnam

Novis in cooperation with AHBT and Phuc Khang Hung organized a knowlege forum on mitigating the risk of emerging swine viral diseases in Hanoi and HCMC, Vietnam. Delegates were introduced to the importance of feed biosecurity incorporating ACTIVATE® DA as a feed acidifier and FORMYCINE® GOLD Px for feed hygiene solution.

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